국가연구개발성과
논문 (학술지)
Effectiveness and safety of Injinoryung-San-Gagambang (Yinchen Wuling powder) decoction on stroke patients with elevated serum liver enzymes Three case reports
| 등록번호 | - | SCI 구분
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※구분 : SCI(SCIE포함), 비SCI |
SCI |
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| 저자명 (주·공동저자) | Chu Hongmin; 한창현 ; 김은석; 공혜진; 윤광식; 전주현; 강재희; 이현; 권오진; 정소영 ※ 과제 참여정보와 일치하는 연구자 상세정보로 정확하지 않을 수 있습니다. 동일저자 논문보기 |
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| 논문구분 | 국외전문학술지 | 학술지명 | MEDICINE |
| ISSN | 0025-7974 | 학술지 출판일자 | - |
| 학술지 볼륨번호 | 97 | 논문페이지 | 0 ~ 0 |
| 학술지 임팩트팩터 | 2.028 | 기여율 | 100 % |
| DOI | 10.1097/MD.0000000000013577 | ||
| 초록 | Background: In Korea, as the number of patients suffering from back and/or leg pain with lumbar disc herniation (LDH) is increasing, the conservative treatments for LDH have been spotlighted. Several studies on the acupotomy have been published, but most of them are only case studies. Therefore, the purpose of this study is to evaluate the effectiveness and safety of acupotomy treatment for the patients with LDH, compared with those of manual acupuncture treatment. Methods/design: This study is planned as a multicenter, parallel design, and RCT. The 146 patients diagnosed with LDH will be are randomly assigned to either the acupotomy group or the manual acupuncture group at a 1: 1 ratio. Participants in both group will receive Each group will received a total of 4 interventions for 2 weeks with either the acupotomy treatment or the manual acupuncture treatment. The effectiveness assessment that verified by VAS, RMDQ, MMST, EQ-5D and PGIC outcomes, will be is conducted on the baseline and 2, 4 and 6 weeks post randomization. The primary outcome will be is the mean change in VAS for back and/or leg pain 4 weeks post randomization. after 4 weeks on baseline. In addition, the Adverse events will also be are checked every visit. Discussion: The results of this study will provide evidence of effectiveness and safety of acupotomy treatment on LDH. Trial registration: Clinical Research Information Service of South Korea (CRIS- KCT0002824) at 24 April 2018. Abbreviations: AE = adverse events, CRC = clinical research coordinator, CRF = case report form, CT = Computed Tomography, DUCKHD = Daejeon University Cheonan Korean Medicine Hospital, DUDKMH = Daejeon University Dunsan Korean Medicine Hospital, EQ-5D = EuroQol Five Dimensions questionnaire, FAS = Full Analysis Set, LDH = Lumbar Disc Herniation, MCID = Minimal Clinically Important Difference, MMST = Modified-Modified Schober Test, MRI = Magnetic Resonance Imaging, PGIC = Patient Global Impression of Change, PI = Principal Investigator, PP = Per protocol, RCT = randomized controlled trial, RMDQ = Roland Morris Disability Questionnaire, SAE = serious adverse events, VAS = Visual Analog Scale | ||
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