논문 (학술지)
Transformation of animal genomics by next-generation sequencing technologies: a decade of challenges and their impact on genetic architecture
| 등록번호 | RPMS-2019-0190752107 | SCI 구분
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※구분 : SCI(SCIE포함), 비SCI |
SCI |
|---|---|---|---|
| 저자명 (주·공동저자) | Ghosh Mrinmoy; Sharma Neelesh; Singh Amit Kumar; Gera Meeta; Pulicherla Krishna Kanth; Jeong Dong Kee | ||
| 논문구분 | 국외전문학술지 | 학술지명 | CRITICAL REVIEWS IN BIOTECHNOLOGY |
| ISSN | 0738-8551 | 학술지 출판일자 | - |
| 학술지 볼륨번호 | 38 | 논문페이지 | 1157 ~ 1175 |
| 학술지 임팩트팩터 | 6.542 | 기여율 | 100 % |
| DOI | 10.1080/07388551.2018.1451819 | ||
| 초록 | For more than a quarter of a century, sequencing technologies from Sanger’s method to nextgeneration high-throughput techniques have provided fascinating opportunities in the life sciences. The continuing upward trajectory of sequencing technologies will improve livestock research and expedite the development of various new genomic and technological studies with farm animals. The use of high-throughput technologies in livestock research has increased interest in metagenomics, epigenetics, genome-wide association studies, and identification of single nucleotide polymorphisms and copy number variations. Such studies are beginning to provide revolutionary insights into biological and evolutionary processes. Farm animals, such as cattle, swine, and horses, have played a dual role as economically and agriculturally important animals as well as biomedical research models. The first part of this study explores the current state of sequencing methods, many of which are already used in animal genomic studies, and the second part summarizes the state of cattle, swine, horse, and chicken genome sequencing and illustrates its achievements during the last few years. Finally, we describe several high-throughput sequencing approaches for the improved detection of known, unknown, and emerging infectious agents, leading to better diagnosis of infectious diseases. The insights from viral metagenomics and the advancement of next-generation sequencing will strongly support specific and efficient vaccine development and provide strategies for controlling infectious disease transmission among animal populations and/or between animals and humans. However, prospective sequencing technologies will require further research and in-field testing before reaching the marketplace. | ||
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