- 성과
- 논문 (학술지) Analysis of 13 Banned Colorants in Cosmetics via Liquid Chromatographic and Mass Spectrometric Techniques
등록번호 | - |
SCI 구분
※구분 : SCI(SCIE포함), 비SCI
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SCI |
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저자명 (주·공동저자) | Kyoung-Moon Han You Kyung Kim; Sowoon Seo Jun Hyoung Kim Ji Hyun Lee; Sooyeul Cho | ||
논문구분 | 국외전문학술지 | 학술지명 | Applied Sciences-Basel |
ISSN | 2076-3417 | 학술지 출판일자 | 2023-05-12 |
학술지 볼륨번호 | 13 | 논문페이지 | 5967 ~ 5967 |
학술지 임팩트팩터 | 2.838 | 기여율 | 0 % |
- 초록
- Even though synthetic colorants can cause side effects such as allergies and pigmentation, they have not been sufficiently researched. Herein, high-performance liquid chromatography, liquid chromatography-tandem mass spectrometry, and liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS) were used to detect 13 banned synthetic colorants in cosmetics and characterize their fragmentation. The developed HPLC method was validated following the International Conference on Harmonisation guidelines (specificity, limit of detection, limit of quantification, recovery, linearity, accuracy, and precision) and applied to 120 distributed cosmetic products, one of which was found to contain three illegal synthetic colorants, namely Basic Blue 26 (0.33 mg/g), Basic Red 2 (0.53 mg/g), and Basic Yellow 28 (31.50 mg/g). Additionally, based on their fragment ions obtained using LC-Q-TOF-MS, the fragmentation pattern of synthetic colorants was predicted. Thus, our work paves the way for the reliable detection of illegal synthetic colorants and may help to prevent the distribution of cosmetics containing the same.
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